Bart De Moor

Research

Teaching and Research

• Scientific discipline: numerical linear algebra, dynamical systems theory and modelling, advanced control theory, datamining and bioinformatics 
•  Courses: Computer Aided Control System Design and Dynamical Systems 
•  Research group: currently promoter of ten PhD students and six postdocs
• Past thesis advisor of seventy PhD students, all worldwide active in academia, industry, government agencies 
• Co-published more than 400 scientific papers and contributed to ten books
• Coordinator of research projects, financed by regional, Belgian and European funding agencies, many of them with colleagues from other disciplines (micro-climate simulations, riverbasin control, industrial process control, bioinformatics, genomics, proteomics, oncology, gynaecology, intensive care (see www.bartdemoor.be for publications))
• Regularly member of PhD jury’s in Belgium and abroad and invited speaker at international congresses
• Scientific director of the Future Health Department of the Flanders Strategic Research Institute iMinds (software for genomics applications and clinical decision support systems)
• Co-founder of KU Leuven SCORES and BioSCENTer
• Co-founder of 6 ‘spin-off’ companies, 4 of which still active: IPCOS (industrial process control), TML (traffic modelling and consulting), D-square (datamining in the process industry), Cartagenia (genomics data analysis)
• Co-holder of several patents

Current research team

Laura Alonso Padula, Alexandre Arnould, Fernando Crema Garcia, Sarthak De, Femke De Backere, Jaldert François, Axel Geysels, Sibren Lagauw, Oliver Lauwers, Giulia Rinaldi, Zahrasadat Sajjadifar, Vincent Scheltjens, Konstantinos Theodorakos, Yoeri Uyttendaele, Hans Van Rooij, Thomas Vanhemel, Lukas Vanpoucke, Christof Vermeersch, Sem Viroux, Lyse Naomi Wamba Momo, Wanqiu Zhang

Biography

Positions

• 2000-now: Full Professor, Dept. Electrical Engineering, KU Leuven, Belgium
• 2016-now: Guest Professor, Dept. Information Engineering & Mathematics, Universita Di Siena, Italy
• 2010-2015: Scientific Director Department Medical IT, Strategic Research Center iMinds, Flanders
• 2009-2013: Vice-rector International Policy, KU Leuven
• 2007-2009: Head Socio-Economical Cabinet, Minister-President Flanders Region (Y. Leterme)
• 1994-1999: Main Science Advisor, Minister-President Flanders Region (L. Van den Brande)
• 1992: Visiting Research Associate, University of Minneapolis, USA
• 1991-1992: Head of Cabinet, Federal Minister of Science Policy (W. Demeester), Brussels
• 1990-1999: Senior Research Associate, Scientific Research Foundation (FWO), Flanders
• 1988-1990: Research Associate at Stanford University (depts. Electrical Engineering (Thomas Kailath) and Computer Science (Gene Golub))
• 1983-1988: PhD Grant IWONL (Institute for Scientific Research in Industry and Agriculture)

Fellowships, Awards, Honors

• 2020: Commander in the Order of King Leopold I, granted by King Filip of Belgium 
• 2020: ERC Advanced Grant ‘Back to the roots’
• 2018-now: Co-holder KU Leuven Chair ‘Health Care Systems Quality and Accessibility’, endowed by Health Insurance Organisation CM
• 2017: Fellow SIAM for ‘Contributions to numerical multilinear algebra’
• 2010: Excellence Award of the Flanders Research Foundation, by King Albert II of Belgium
• 2003: Fellow IEEE for ‘Contributions to algebraic/numerical methods for systems and control’
• 1999: IEEE Signal Processing Society Award
• 1996: Automatica Award, International Federation of Control (IFAC)
• 1994: Bi-annual Siemens Award by the Flanders Research Foundation
• 1992: Laureate of the Royal Academy of Belgium for Sciences and Arts
• 1990: Guillemin-Cauer Award IEEE Transactions Circuits and Systems
• 1989: Leslie Fox Prize, Cambridge, UK
• 1986: Leybold-Heraeus Prize

Research Activities

Scientific Disciplines:

• Numerical (multi-) linear algebra and algebraic geometry (generalized singular value decompositions, multi-dimensional SVD, generalized linear complementarity problems, quantum information theory, numerical linear algebra approach to rooting sets of polynomial equations)
• Dynamical System Theory and Identification, data science, machine learning (subspace identification, support vector machines)
• Advanced Control Theory (observers, computer aided control system design)

Application Areas:

• Industry 4.0: Subspace system identification and control of the synthesis section of a Urea plant, of the dipping section of a capsule manufacturing process,  data driven identification of several Belgian river basins (flood avoidance), forecasting models for indoor CO2 concentration, modelling (prevention of) flutter for airplane wings, model-based data assimilation for microclimate air-quality forecasting, smart grid Belgian electrical load forecasting (3000 transformers, sampled every 15 min during 5 years)
• Medical decision support systems (DSS): Belgian health insurance prescription records analysis, automation of intensive care DSS, algorithms for automated PCR analysis, hospital prediction of duration stay software

Publications: Books, papers, other

• See www.bartdemoor.be
• Search engine on https://homes.esat.kuleuven.be/~sistawww/cgi-bin/pub.pl
• Google Scholar https://scholar.google.com/citations?hl=en&user=qws2WIMAAAAJ

Bibliometry

• https://scholar.google.com/citations?hl=en&user=qws2WIMAAAAJ: 86 675 citations; H-index 124;
• Web of Science: H-index 72; Total cited: 21 482 (without self-citation: 20 904)
• Ranked 15th all-time top PhD advisors in mathematics (https://genealogy.math.ndsu.nodak.edu/extrema.php)
• Ranked 76th worldwide and ranked 1st  for Belgium in top H-index for Computer Science and Electronics (http://www.guide2research.com/scientists/)

Mentorship:

• 1991-now: Promotor of 82 PhD theses (see Mathematical Genealogy), all worldwide active in academia (30%), industry (60%), government agencies (10%)
• 1991-now: Host to 46 postdoctoral researchers and visiting professors
• 1991-now: Promotor of 200+ master theses in masters mathematical engineering, statistics, artificial intelligence, bioengineering, electrical engineering

Coordinator of and contributor to numerous research projects, funded by regional, Belgian and European funding agencies and third parties (full list www.bartdemoor.be)

Reviews:

• Regular reviewer for journals of IEEE, SIAM, IFAC and their major conferences, regular proposal reviewer for Belgian and European Funding Agencies and jury member

Science Outreach

• 2019: Co-founder of Math popularizing website
• 2016-now: patron of STEM Training Website
• 2015-now: Founder & Chairman Board of Health House (high-tech health experience center)
• 2015-2017: Member of the Flanders STEM Platform
• 2009-now: Patron STEM Olympiad
• 2009-now: Trustee of the RVO-Society
• 2005 & 2015: Teacher KU Leuven Children’s University
• 2002-now: Regular guest appearances in science outreach programs on national radio and television
• 1992-now: Co-founder interdisciplinary philosophical think-tank Worldviews

Organisation of Scientific meetings

• 1997: Program Chairman of European Control Conference, Brussels, 750 attendees, 2004
• 2004: Chair of the Conference of Mathematical Theory of Networks and Systems, Leuven, 600 attendees
• 2019: Organizer of the Benelux Meeting on Systems and Control, Houthalen, 150 attendees,
• At numerous occasions: Member of the organizing/program committees of the Conference on System Identification (SYSID), European Control Conference (ECC), Benelux meeting on Systems and Control, …

Technology Transfer

My contribution to our university KU Leuven being ranked 7th in the Thomson-Reuters ranking of most innovative universities in the world (1st in Europe), has been the creation of 10 spinoff/start-up companies:

• www.ipcos.com (industrial process control, management buy-out)
• www.tmleuven.be  (traffic modelling and consulting)
• Data4s (fraud detection (mobile phones, credit cards, tax evasion), acquired by Norkom next by BAE Systems
• Silicos (drug discovery, closed-down)
• www.trendminer.com  (data mining in the process industry, acquired by Software AG)
• Cartagenia (genomics data analysis, acquired by Agilent)
• www.ugentec.com  (automated PCR analysis)
• www.lindacare.com  (patient tele-monitoring)
• https://www.aspect-analytics.com (software for mass spectrometry imaging).
• https://www.timeseer.ai (monitoring time series in the process industry)

Patents: Co-holder of several patents

Member of the Advisory Committee of the Capricorn Health-tech Investment Fund

Institutional Responsibilities

• 2021-present: Member of the Board of ‘Ignatius in Beweging’ (Jesuit School Network)
• 2020-present: Chairman of the Board of Capricorn Digital Growth Fund (CDGF, venture capital)
• 2019-present: Member of the Board of UCSIA  (Jesuit Academic Foundation)
• 2017-present: Founding Chairman of Health House (high-tech health experience center)
• 2015-present: Member Steering Group Leuven Mindgate
• 2014-present: Member of the Board of Officenter
• 2009-present: Chairman Alamire Foundation (Center for the Study of Polyphonic Music)  
• 2009-2014: Founding Board member Leuven International School
• 2009-2013: Chairman Committee Internationalisation & Development Cooperation Flemish University Council
• 2009-2013: Member of the Board KU Leuven
• 2007-2015: Chairman Industrial Research Fund KU Leuven
• 2007-2011: Board member iMinds  (merged since 2017 with imec)
• 2007-2015: Chairman Board Hercules Foundation (scientific infrastructure funding agency, merged in 2015 with FWO)
• 2000-2005: Board member Belgian Nuclear Research Center, Belgium
• 1999-now: Secretary Board (till 2015), Member Scientific Committee of Technopolis (Flanders Children’s Science Experience Center)
• 1995-now: Member Board, remuneration, investment, strategic committees: Flanders Biotech Research Institute

Commission of Trust

• 2018-present: Scientific architect and coordinator of Flanders AI Program (32 mio €/year), involving universities, research institutes and industry
• 2020-present: Chairman of the Board of FAIA (Flanders AI Academy)
• 2018-present: Member ESGAB (European Statistical Governance Advisory Board, nominated by the European Council decision 18/12/2017 (2017/C 439/03))
• 2017-2018: ‘Sherpa’ for Belgium in the European High Performance Computing Initiative
• 2016-2018: Member of the Scientific Advisory Committee of Science Europe
• 2016-present: Member Int. Scientific Advisory Board of Wallenberg Autonomous Systems Program, Knut and Alice Wallenberg Foundation
• 2014-present: Member Board AstraZeneca Foundation
• 2013-present: Member Board Trustees Danish National Research Foundation

Assessments:

• 2021: Member of the assessment committee of KTH, Stockholm
• 2020-2021: Chairman of the assessment committee of the Electrical Engineering Institute Nicola Tesla
• 2015-2019: Chairman University Research Policy Assessment Committee, Finish Academy of Sciences
• 2016-2019: Member committee of the Villum Young Investigator Grants of the Velux Foundation, Denmark
• 2015-present: Member of committees in the Swedish, Norwegian, Irish and Luxembourg Science/Research Councils
• 2013-2020: Member Panel Starters Grant Computer Sciences European Research Council
• 2013-2014: Member National Tenure Track Commission for Control and Automation in Italy
• 2010-2012: Chairman of the Education Assessment Panel (for NVAO) as well as the Research Assessment Panel of Electrical Engineering University Departments in The Netherlands
• 2006-2008: Selection Committees member for Linnaeus Centers of Excellence (Sweden) and UNIK (Denmark)

Memberships of Societies

• Fellow of the Institute for Electrical and Electronic Engineers
• Fellow of the Society for Industrial and Applied Mathematics
• Member of the American Mathematic Society
• Member of the International Federation of Automatic Control
• Elected member Royal Academy of Belgium for Sciences and Arts
• Member of VIRA (Organisation of Belgian diplomates and international representatives)
• Member of ie-net (Flanders Engineering Association)
• Member of ‘Academische Stichting Leuven’

Active projects

• Tensor Tools for Taming the Curse
• Ondersteuning van diagnostiek bij neuropsychiatrische aandoeningen op oudere leeftijd via machine learning classificatie van klinische, neuropsychologische en neuroimaging data.
• Back to the Roots - Back to the roots of data-driven dynamical system identification
• ENZYMARES - Enzyme prediction toolbox
• FAIR 2-0 - AI Research Program
• FLIPR-MDR-IDN - Quality improvement in inguinal hernia surgery by analysis of big data with implementation of the MDR legislation
• Idea-Musa Subcontracting for C2 - Optimal Planning of Surgery for Gynaecologyc Patients

Finished projects

• Biomarker discovery in endometriosis using a transcriptomic/proteomic approach
• Patient-tailored treatment for patients with rectal cancer
• Implementatie van een niet-lineair Model Predictive Control Sturingssysteem voor het Demerbekken
• Direct detection and identification of neuro-oncology markers in brain tumours
• Novel strategies for organ sparing in patients with complete response to radiochemotherapy in Iocally advanced rectal cancer
• Data4Growth
• Can response to Epidermal Growth Factor Receptor antibodies in patients with metastatic Colorectal Cancer be predicted?
• Cost Action BM 1104 Mass Spectrometry Imaging : New Tools for Healthcare Research
• Determining genetic markers for platinumsensitivity in ovarian cancer
• TML
• Data-driven modeling techniques for indoor CO2 estimation
• Endometrial cancer diagnosis based on predictive computer models within an International Endometrial Tumour Analysis (IETA) collaboration
• Aging_Swine - Aging, the metabolic syndrome and cardiovascular diseases: study in the swine.
• Aida - AI tools for Curation of Clinical registries
• AMBioRICS - Algorithms for Medical and Biological Research, Integration, Computation and Software
• BIL00/17/Polen - BoF- BIL00/17/Polen
• BIL99/18 - Identification of linear and nonlinear systems
• BioMaGNet - Bioinformatics and Modeling: from Genomes to Networks
• BIOPATTERN - Computational intelligence for biopattern analysis in support of e-Healthcare.
• BIOPTRAIN - Bioinformatics & Optimisation Training
• BioScope-IT - Bioinformatics Service project
• Bonatema -Ontologies - Development of an ontology-based biological knowledge system for the acquisition of prior knowledge for use in bioinformatics algorithms
• CDM - Clinical Data Miner - an electronic data capture software framework for supporting clinical research
• City of Things - Slimme IoT technologie gekoppeld aan slimme zorgverlening voor levensloopbestendig wonen
• CLIMAQs - Climate Impact and Air Quality Modelling for Policy Support
• Clinicoproteomics - A clinicoproteomic study of patients with cervical and endometrial malignant tumours
• DSquare - D Square Data Mining
• Dynamical Systems - Dynamical systems and control: computation, identification and modelling.
• DYSCO I - Dynamical systems, control and optimization
• DYSCO II - Dynamical systems, control and optimization
• EC-EDITH - European doctorate on information technology
• Endometriosis Test - Development of a Noninvasive Diagnostic Test for Endometriosis
• endometriosis-proteomics - Noninvasive diagnosis of endometriosis based on plasma proteomics analysis
• FAIR - AI Research Program
• Flight Test Easy+ - Optimised design engineering process for aerospace structures
• Functional Genomics - Identification of novel functions, components and target genes for Sch9-or PKB-mediated signal transduction.
• FWO - Development of algorithms for datamining in micro array experiments in oncology.
• GENAGRID - Bioinformatic services for genetic association studies using high-performance grid computation
• Genetic Network Inference - Development of a generic methodology for genetic network inference
• Glycemie - Development of a control system for the optimization of glycemia in critically ill patients
• Glycemie_2 - Optimization and implementation of a control system aiming the normalization of glycemia of critically ill patients
• IBD4Health summer school 2017 - Big Data Challenges for Healthy Living and Active Aging
• IM Nick Smisdom - Data highway to precision medicine
• iMinds SBO dotatie - iMinds Medical Information Technologies- SBO (dotatie)
• IOTA 3 Ovarian tumour characterisation - Multicentre prospective assessment study on the pre-operative characterisation of ovarian tumours based on predictive computer models
• IOTA-AI - AI-assisted automated detection of ovarian cancer on ultrasound imaging
• IPoC C2 - Subcontracting - BDM - Immune profiling of CIDP (IPoC)
• KOTK Next-generation multiplex pathology - Next-generation multiplex pathology: enabling precision medicine by improving cancer diagnostics and biomarker identification
• LOGIC-insulin - Clinical validation and filing for regulatory approval of a blood glucose regulator for the Intensive Care Unit
• MaNet - Mathematical engineering tools for Networks: Data driven mining, identification, control and optimization
• McKnow - Automated and User-Oriented Methods and Algorithms for Knowledge Management
• MicroArray - Ovarian cancer management using microarrays
• MIDAS - Meaningful Integration of Data, Analytics and Services
• MIPS - Engineering concepts and mathematics for model-based information processing systems MIPS
• Monsanto - Softwarelicentie INCLUSive Software
• MOOC - New MOOC - Data Analytics in Health
• MSIpad - Mass Spectrometry Imaging for pathology and drug discovery
• Multilinear SVD - Multilinear generalizations of the singular value decomposition and applications in signal processing and systems identification
• MyHealthData - MyHealthData Scenarios for a patient s use of healthcare data
• nD - nD: Multidimensional dynamical systems, multi-linear numerical algorithms and tensor data
• Network inference - Robust algorithms for regulatory network inference based on expression measurements and biological a prioir information
• Neural circuits - Application of system identification tools to neural circuits
• Nonlinear Identification - Identification of nonlinear systems and its applications to microwave systems.
• Omics based clinical decision support - Large scale and online computing to advance (omics-based) clinical decision support and life sciences research
• P4/02-Modelling - Modelling, identification, simulation and control of complex systems (electrotechnical part)
• PASCALe - Platform voor het Annoteren en Structureren van Content en Analyse van het Leergedrag
• PROMETA - A proteomics center as part of the interfaculty center for proteomics and metabolomics.
• prostaatcarcinoom - “Implementation of functional imaging and molecular diagnostics for patienttailored treatment of prostate cancer”
• prostate cancer - Towards the identification of the true high-risk prostate cancer patient
• QIT - Quantum Informatics
• Quantum - Developing new quantum algorithms
• QUPRODIS - Quantum properties of distributed systems
• Rectal Cancer - Response prediction of rectal cancer based on molecular and functional characteristics of the tumor.
• Robust MHE - Moving horizon estimation: robust stability, robust performance and interaction with model predictive control
• Robust Statistics - Integration of parametric robust methods and non-parametric kernel based methods.
• SCORES4CHEM - Safety, Control, and Optimization: Research, Education and Services for the Chemical Industry
• SeLMA - Structured Low-Rank Matrix/Tensor Approximation: Numerical Optimization-Based Algorithms and Applications
• Side Channels - The application of advanced techniques for system identification to study side channels for cryptographic algorithms: cryptanalysis and design
• SILICOS - Research towards an in silico drug discovery platform (Virtual Screening Factory) based on Spectrophore™ technology
• SQUAD - Molecular and computational biology of quorum signaling in bacterial pathogens: Salmonella
• Subfunctionalization - Development of a computational method for studying subfunctionalization by transcriptional divergence of duplicated plant genes.
• SVM and kernel methods - Support Vector Machines and Kernel Based Learning: Advanced Algorithms
• SVM-Theory - Support vector machines and kernel methods : theory, algorithms and applications
• SymBioSys I - K.U.Leuven Center for Computational Systems Biology
• The Leuven Chansonnier - Researching and Valorizing Franco-Flemish Polyphony with High-High-Technology Tools
• The Library of Voices - The Library of Voices - Unlocking the Alamire Foundation’s Music Heritage Resources Collection through Visual and Sound Technology
• The sound of music - Innovative research and valorization of plainchant through digital technology
• TRAFFIC - Sustainability effects of traffic management systems
• VitaminD - Identification of genes and their regulatory motifs that are involved in antiproliferative signaling induced by 1,25-dihydroxyvitamin D3 or in the tissue-selective activity of vitamin D analogs.
• WOG-ANMMM - Advanced numerical methods for mathematical modelling.

Awards

• Best Paper Award at the IEEE International Workshop on Artificial Intelligence for Health - 2023
• IFAC Fellow Award
• Fellow SIAM (2017)
• Excellentieprijs FWO
• Promotor for an honorary degree awarded to Prof. Dr. Lennart Ljung
• IEEE Signal Processing Society Best Paper Award
• Tri-annual best paper award of Automatica
• Bi-annual Siemens prize
• Promotor for an honorary degree awarded to Prof. Dr. Gene Golub
• Laureate of the Belgian Royal Academy of Sciences
• Guillemin-Cauer Best Paper Award
• The Leslie Fox Prize
• Leybold-Heraeus Prize

Editorship

• Associate Editor of the IEEE Transactions on Signal Processing
• Journal A (Systems and Control Journal for Benelux branch of IFAC)
• Systems and Control Letters
• Applied and Computational Control, Signals and Circuits
• The Journal of the Franklin Institute
• 'Onze Alma Mater'

Membership

• 2020 Laureate of the Royal Flemish Academy of Belgium for Sciences and Arts (KVAB) in the Class of Technical Sciences since October 2023
• Ondervoorzitter Algemene Vergadering Flamenco since January 2012
• Voorzitter Industriel Onderzoeksfonds since January 2009
• Voorzitter Herculesstichting since January 2007
• Raad van Bestuur : Alamire Stichting, VIB, VCBT, Center Leo Apostel since January 2004
• Bestuurslid : Worldviews, EUCA, BIRA, VILv, ERCIM since January 2004
• Lid : VRT Adviescommise O&I, KVAB (klasse technische wetenschappen), Roger Van Overstraeten Society, Vlaanderen in Actie (Coördinatie comité), Club of Rome, Center Leo Apostel, CAWET, IFAC, IEEE technical Committee on Robust Control, The American-Europea since January 2004
• Jury Member : Abilitazione Commission Italy (2013), Chairman Onderzoeksvisitatie Nederland, Member International Committee of Danish Centers of Excellence since January 2004
• Peterschap : Vlaamse Technologie Olympiade en Vlaamse Jeugd Technologie Olympiade since January 2004
• Scientific advisory committee of Technopolis, the Flemish Children Science and Technology Center (www.technopolis.be) since January 2001
• Research Policy Council of the Katholieke Universiteit Leuven since January 1999

Honours

• Order of Leopold I
• ERC Advanced Grant

Publications

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