SQUAD - Molecular and computational biology of quorum signaling in bacterial pathogens: Salmonella
From 01-10-2002 to 28-02-2007
Description
The acquirement of resistance of pathogenic bacteria to common antibiotics and the development of multidrug resistant strains is raising alarms in healthcare and fueling demand for new antibiotics. Moreover, antibiotics have a borad range effect, killing also the beneficial intestinal microflora. Alternative more sustainable approaches to cope with these infectious bacteria are needed. An alternative way to combat bacterial infetions could be based on the breakthrough discovery that a wide variety of pathogenic bacteria communicate via a common chemical 'language' required to coordinate and regulate the onset of pathogenesis. This bacterial communication is termed quorum sensing. A major goal of this project is to gain insight into the mechanism of quorum sensing since it indefinitely is the clue to a plethora of distinct intriguing phenomena such as bacterial pathogenesis.Team
- Bart De Moor, Co-promoter
- Kathleen Marchal, Coordinator
- Thomas Dhollander, Team member
- Kristof Engelen, Team member
- Pieter Monsieurs, Team member
- Karen Lemmens, Team member
- Tim Van den Bulcke, Team member (External)
Financing
Funding: IWT - Agentschap voor Innovatie door Wetenschap en Technologie
Program/Grant Type: IWT other - Other IWT Grants
Events
2/09/2024:
PhD defense - Martijn Oldenhof
Machine Learning for Advanced Chemical Analysis and Structure Recognition in Drug Discovery
3/09/2024:
Meet the Jury Igor Tetko on Advanced Machine Learning in Drug Discovery
12/09/2024:
Multimodal analysis of cell-free DNA for sensitive cancer detection in low-coverage and low-sample settings
Seminar by Antoine Passemiers
News
STADIUS Alumni Herman Verrelst – new CEO of Biocartis
08 June 2017
Herman Verrelst, the founder of KU Leuven spin-off Cartagenia, who has been working in Silicon Valley, US for the last few years will be returning to Belgium to follow the steps of Rudi Pauwels as CEO of the Belgian diagnostic company, Biocartis.
Supporting healthcare policymaking via machine learning – batteries included!
29 May 2017
STADIUS takes the lead in the data analytics efforts in an ambitious European Project MIDAS.
Marc Claesen gives an interview about his PhD for the magazine of the Faculty of Engineering Sciences "Geniaal"
10 February 2017
Did you know that in Belgium approximately one third of type 2 diabetes patients are unaware of their condition?
Joos Vandewalle is nieuwe voorzitter KVAB
09 October 2016
Op 5 oktober 2016 heeft de Algemene Vergadering van de Academie KVAB Joos Vandewalle verkozen tot voorzitter van de KVAB.