Functional Genomics - Identification of novel functions, components and target genes for Sch9-or PKB-mediated signal transduction.
From 01-01-2004 to 31-12-2007
Description
Protein kinase B (Akt1) has a primary role in the regulation of growth and profliferation of mammalian ceels. In the yeast Saccharomyces cerevisiae, this function appears to be fulfilled by the protein kinase Sch9. In this project we'll make use of conditional lethal mutant yeast strains for which growth is entirely dependent on Sch9 activity in order to identify novel downstream signaling components and their respective targets making use of classical epistasis analyses as well as genome wide microarray studies.Team
- Kathleen Marchal, Coordinator
- Bart De Moor, Promoter
- Kristof Engelen, Team member
- Karen Lemmens, Team member
Financing
Funding: FWO - Research Foundation - Flanders
Program/Grant Type: FWO Research Grant - FWO Research Grant
Events
2/09/2024:
PhD defense - Martijn Oldenhof
Machine Learning for Advanced Chemical Analysis and Structure Recognition in Drug Discovery
3/09/2024:
Meet the Jury Igor Tetko on Advanced Machine Learning in Drug Discovery
12/09/2024:
Multimodal analysis of cell-free DNA for sensitive cancer detection in low-coverage and low-sample settings
Seminar by Antoine Passemiers
News
STADIUS Alumni Herman Verrelst – new CEO of Biocartis
08 June 2017
Herman Verrelst, the founder of KU Leuven spin-off Cartagenia, who has been working in Silicon Valley, US for the last few years will be returning to Belgium to follow the steps of Rudi Pauwels as CEO of the Belgian diagnostic company, Biocartis.
Supporting healthcare policymaking via machine learning – batteries included!
29 May 2017
STADIUS takes the lead in the data analytics efforts in an ambitious European Project MIDAS.
Marc Claesen gives an interview about his PhD for the magazine of the Faculty of Engineering Sciences "Geniaal"
10 February 2017
Did you know that in Belgium approximately one third of type 2 diabetes patients are unaware of their condition?
Joos Vandewalle is nieuwe voorzitter KVAB
09 October 2016
Op 5 oktober 2016 heeft de Algemene Vergadering van de Academie KVAB Joos Vandewalle verkozen tot voorzitter van de KVAB.
