Financing: Research Foundation - Flanders (FWO)

Project reference Nr.: G.0241.04
Start: 2004-01-01
End: 2007-12-31

Description:
Protein kinase B (Akt1) has a primary role in the regulation of growth and profliferation of mammalian ceels. In the yeast Saccharomyces cerevisiae, this function appears to be fulfilled by the protein kinase Sch9. In this project we'll make use of conditional lethal mutant yeast strains for which growth is entirely dependent on Sch9 activity in order to identify novel downstream signaling components and their respective targets making use of classical epistasis analyses as well as genome wide microarray studies.
 

SMC people involved in the project:

• Kathleen Marchal (Coordinator)
• Bart De Moor (Promoter)
• Kristof Engelen (Team member)
• Karen Lemmens (Team member)