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Tcfamily:Electrochemical Potential-driven transporters
From Ytpdb
- Electrochemical Potential-driven transporters (226)
- Channels/pores (22)
- Primary Active Transporters (37)
- Group Translocators (2)
- Transport Electron Carriers (0)
- Accessory Factors Involved in Transport (0)
- Incompletely Characterized Transport Systems (4)
- Protein not classified in TC (7)
Yeast permeases in TC family Electrochemical Potential-driven transporters
| Gene name | Description | Sublocation |
|---|---|---|
FUN26 
| Broad-specificity nucleoside transporter of internal membranes - similar to human placental equilibrative nucleoside transporter 1 | vacuolar membrane |
| YBR241C
| Protein of the sugar transporter superfamily - unknown biological function | vacuolar membrane |
| VBA2
| Vacuolar transporter involved in vacuolar sequestration of arginine, histidine, lysine and tyrosine - likely acts as an H+ antiporter | vacuolar membrane |
| VBA3
| Vacuolar transporter involved in vacuolar sequestration of histidine and lysine - likely acts as an H+ antiporter | vacuolar membrane |
| MCH1
| Vacuolar transporter similar to mammalian monocarboxylate transporters - unknown biological function | vacuolar membrane |
| VCX1
| Vacuolar Ca++/H+ exchanger | vacuolar membrane |
| VBA4
| Putative substrate-H+ antiporter - unknown biological function | vacuolar membrane |
| AVT6
| Transporter mediating the release of glutamate and aspartate from the vacuole to the cytosol | vacuolar membrane |
| SYG1
| Putative transport protein of inner membranes | vacuolar membrane |
| AVT7
| Protein similar to plant amino-acid transporters and mammalian vesicular GABA transporter - unknown function | vacuolar membrane |
| AVT1
| Transporter essential for the uptake of tyrosine, glutamine, asparagine, isoleucine and leucine in isolated vacuoles | vacuolar membrane |
| AVT3
| Transporter mediating the release of tyrosine, glutamine, asparagine, isoleucine and leucine from the vacuole to the cytosol | vacuolar membrane |
| ZRT3
| Vacuolar zinc efflux protein | vacuolar membrane |
| GEX2
| Plasma membrane and vacuolar membrane glutathione/H+ antiporter | vacuolar membrane |
| SMF3
| Vacuolar protein similar to the Smf1 manganese transporter - proposed role in mobilization of vacuolar iron | vacuolar membrane |
| CCC1
| Proposed vacuolar iron transport protein | vacuolar membrane |
| VBA1
| Vacuolar transporter involved in vacuolar sequestration of lysine and histidine - likely acts as an H+ antiporter | vacuolar membrane |
| ZRC1
| Vacuolar transporter of zinc (and possibly other metals) | vacuolar membrane |
| AVT4
| Transporter mediating the release of tyrosine, glutamine, asparagine, isoleucine and leucine from the vacuole to the cytosol | vacuolar membrane |
| VNX1
| Vacuolar Na+(K+)/H+ exchanger | vacuolar membrane |
| YOL092W
| Protein similar to the human lysosomal CTNS cystine transporter mediating H+-driven cystine export from lysosomes - unknown function | vacuolar membrane |
| MCH4
| Protein similar to mammalian monocarboxylate transporters - unknown biological function | vacuolar membrane |
| COT1
| Vacuolar zinc (and possibly other metals) transporter | vacuolar membrane |
| NCR1
| Vacuolar transport protein involved in sterol homeostatis and trafficking | vacuolar membrane |
| YDR352W
| Protein similar to the human lysosomal CTNS cystine transporter mediating H+-driven cystine export from lysosomes - unknown function | vacuolar membrane |
| YHC3
| Vacuolar membrane protein with proposed role in arginine tranport - mutations in the human ortholog (Btn1) causes Batten disease | vacuolar membrane |
| ATG22
| Vacuolar membrane transporter catalysing efflux of amino acids during autophagy | vacuolar membrane |
| FLX1
| Protein involved in transport of FAD from the cytosol into the mitochondrial matrix | mitochondrial membrane |
| GOG5
| Nucleotide-sugar permease of the Golgi - promotes transport of GDP-mannose | Golgi membrane |
| KHA1
| Intracellular (probably Golgi apparatus) antiporter | Golgi membrane |
| HUT1
| UDP-galactose transporter located in the Golgi | Golgi membrane |
| ANT1
| Peroxisomal transporter of adenine nucleotides (ATP, AMP) - member of the mitochondrial carrier family (MCF) | peroxisomal membrane |
| PET9
| ADP/ATP carrier protein- member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| AAC3
| ADP/ATP carrier protein - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| RIM2
| Mitochondrial CTP/CMP, TTP/TMP and UTP/UMP exchange protein - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| CTP1
| Mitochondrial citrate transporter - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| YDL119C
| Protein of the mitochondrial carrier family (MCF) - unknown function | inner mitochondrial membrane |
| YHM1
| Mitochondrial GTP/GDP exchange protein - member of the mitochondrial carrier family (MCF) | inner mitochondrial membrane |
| YEA6
| NAD+ carrier of the inner mitochondrial membrane | inner mitochondrial membrane |
| PIC2
| Phosphate carrier of the inner mitochondrial membrane | inner mitochondrial membrane |
| TPC1
| Mitochondrial thiamine pyrophosphate carrier - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| MTM1
| Protein of the mitochondrial carrier family (MCF) - proposed role in transport of a manganese cofactor | inner mitochondrial membrane |
| LEU5
| Mitochondrial coenzyme A transporter- member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| YIA6
| NAD+ carrier of the inner mitochondrial membrane | inner mitochondrial membrane |
| MRS3
| Iron carrier of the inner mitochondrial membrane | inner mitochondrial membrane |
| MIR1
| Phosphate transporter of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| SFC1
| Mitochondrial succinate-fumarate transporter - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| OAC1
| Mitochondrial oxaloacetate and sulfate transporter - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| MRS4
| Iron carrier of the mitochondrial membrane | inner mitochondrial membrane |
| DIC1
| Mitochondrial dicarboxylate transport protein - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| AAC1
| ADP/ATP carrier protein - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| YMR166C
| Protein of the mitochondrial carrier family (MCF) - unknown function | inner mitochondrial membrane |
| MFT1
| Mitochondrial iron transport protein | inner mitochondrial membrane |
| YHM2
| Mitochondrial citrate and oxoglutarate transporter - Protein of the mitochondrial carrier family (MCF | inner mitochondrial membrane |
| PET8
| Mitochondrial S-adenosylmethionine transporter - Member of the mitochondrial carrier family (MCF) | inner mitochondrial membrane |
| SAL1
| Calcium-activated carrier of the inner mitochondrial membrane mediating ATP uptake into the mitochondrial matrix | inner mitochondrial membrane |
| MCH3
| Mitochondrial transporter similar to mammalian monocarboxylate transporters - unknown biological function | inner mitochondrial membrane |
| CRC1
| Mitochondrial carnitine carrier - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| ARG11
| Mitochondrial ornithine carrier - member of the mitochondrial carrier (MCF) family | inner mitochondrial membrane |
| ODC2
| Mitochondrial 2-oxoadipate/2-oxoglurate exchanger - Protein of the mitochondrial carrier family (MCF) | inner mitochondrial membrane |
| ODC1
| Mitochondrial 2-oxoadipate/2-oxoglurate exchanger - Protein of the mitochondrial carrier family (MCF) | inner mitochondrial membrane |
| MFT2
| Mitochondrial iron transport protein | inner mitochondrial membrane |
| YPR011C
| Protein of the mitochondrial carrier family (MCF) - unknown function | inner mitochondrial membrane |
| AGC1
| Mitochondrial glutamate uniporter and aspartate-glutamate exchanger - Protein of the mitochondrial carrier family (MCF) | inner mitochondrial membrane |
| YOR271C
| Protein of the mitochondrial carrier family (MCF) - unknown function | inner mitochondrial membrane |
| NHX1
| Na+/H+ exchanger of the prevacuolar compartment - involved in salt tolerance | late endosome membrane |
| ARN1
| Transporter of ferrichrome-type siderophores | late endosome membrane |
| GEF1
| Chloride channel of Golgi and endosomal compartments | Golgi and endosomal membrane |
| TPO5
| Protein involved in excretion of putrescine and spermidine - present in Golgi and endosomal membranes | Golgi and endosomal membrane |
| MSC2
| Protein similar to the Cot1p and Zrc1p metal vacuolar transporters - affects cellular distribution of zinc | nuclear and ER membrane |
| ARN2
| Transporter of the fungal siderophore triacetylfusarinine C | endosomal membrane |
| AQR1
| Vesicular amino-acid transporter involved in excretion of homoserine, threonine and other amino acids | vesicular membrane |
| YKE4
| Endoplasmic reticulum bidirectional zinc transporter | endoplasmic reticulum |
| ZRG17
| Zinc-regulated transporter of the endoplasmic reticulum | endoplasmic reticulum |
| FUN34
| Protein similar to Ady2, a probable plasma membrane acetate permease | unknown |
| SEO1
| Protein similar to diverse carboxylic acid permeases - unknown function | unknown |
| AVT5
| Protein similar to plant amino-acid transporters and mammalian vesicular GABA transporter - unknown function | unknown |
| RTC2
| Protein similar to the human lysosomal CTNS cystine transporter mediating H+-driven cystine export from lysosomes - unknown function | unknown |
| YBR235W
| Protein similar to Na+-Cl- and Na+-K+-Cl- cotransporters of higher species - unknown function | unknown |
| YCR023C
| Putative substrate-H+ antiporter - unknown biological function | unknown |
| YDL199C
| Protein of the sugar transporter superfamily - unknown biological function | unknown |
| YDL206W
| Protein similar to Ca++/H+ exchangers of various species - unknown function | unknown |
| YDR387C
| Protein of the sugar transporter superfamily - unknown biological function | unknown |
| AVT2
| Protein similar to yeast vacuolar amino-acid transporters - unknown function | unknown |
| HVG1
| Probable nucleotide-sugar permease located in secretion organelles - unknown function | unknown |
| FCY21
| Protein highly similar to purine/cytosine permease | unknown |
| FCY22
| Protein highly similar to purine/cytosine permease | unknown |
| YFL040W
| Protein of the sugar transporter superfamily - unknown biological function | unknown |
| AGP3
| Protein of the amino-acid permease family with proposed role in low-affinity uptake of branched-chain and aromatic amino acids | unknown |
| YFR045W
| Protein of the mitochondrial carrier family (MCF) - unknown function | unknown |
| YGL104C
| Protein of the sugar transporter superfamily - unknown biological function | unknown |
| YGL114W
| Protein similar to tetra- and pentapeptide permease - unknown function | unknown |
| YGR125W
| Protein distantly related to sulfate permeases | unknown |
| YHL008C
| Protein similar to bacterial formate permease - unknown function | unknown |
| YHR048W
| Putative substrate-H+ antiporter - unknown biological function | unknown |
| YIL166C
| Protein similar to diverse carboxylic acid permeases - unknown function | unknown |
| HXT12
| Putative pseudogene derived from an HXT gene | unknown |
| HXT8
| Hxt family protein with intrinsic hexose transport activity - unknown physiological function | unknown |
| ECM27
| Protein similar to Ca++/H+ exchangers of various species - unknown function | unknown |
| YJR124C
| Putative substrate-H+ antiporter - unknown biological function | unknown |
| MCH2
| Protein similar to mammalian monocarboxylate transporters - unknown biological function | unknown |
| YKR105C
| Putative substrate-H+ antiporter - unknown biological function | unknown |
| YLR004C
| Protein similar to diverse carboxylic acid permeases - unknown function | unknown |
| YMR010W
| Protein similar to the human lysosomal CTNS cystine transporter mediating H+-driven cystine export from lysosomes - unknown function | unknown |
| YMR279C
| Putative substrate-H+ antiporter - unknown biological function | unknown |
| APL1
| Protein of the amino-acid permease family associated with low uptake activity for basic amino acids | unknown |
| HXT14
| Protein of the sugar transporter superfamily - able to sustain slow growth on galactose | unknown |
| YOL163W
| Protein similar to diverse carboxylic acid permeases - unknown function | unknown |
| THI72
| Protein with low-affinity thiamine transport capability | unknown |
| SLY41
| Putative transporter of the triose phosphate translocator family - unknown function | unknown |
| YOR378W
| Putative substrate-H+ antiporter - unknown biological function | unknown |
| YPR003C
| Protein similar to sulfate permease - unknown function | unknown |
| YMC1
| Protein of the mitochondrial carrier family (MCF) - unknown function | unknown |
| YJL193W
| Putative transporter of the triose phosphate translocator family - unknown function | unknown |
| ERD1
| Putative transport protein of inner membranes | unknown |
| ERS1
| Protein similar to the human lysosomal CTNS cystine transporter mediating H+-driven cystine export from lysosomes - unknown function | unknown |
| FMP42
| Probable membrane transporter with distant similarity with MFS (Major Facilitator Superfamily) proteins | unknown |
| YMR155W
| Probable membrane tranporter with distant similarity with Mch transport proteins | unknown |
| YNR062C
| Probable membrane transporter with distant similarity with MFS (Major Facilitatir Superfamily) proteins | unknown |
| YBR287W
| Probable membrane tranporter with distant similarity with plant auxin efflux proteins | unknown |
| YLR152C
| Probable membrane tranporter with distant similarity with plant auxin efflux proteins | unknown |
| YNL095C
| Probable membrane tranporter with distant similarity with plant auxin efflux proteins | unknown |
| ECM3
| Probable membrane tranporter with distant similarity with plant auxin efflux proteins | unknown |
| GUP1
| Protein involved in glycerol uptake - unknown function | plasma membrane |
| GUP2
| Protein involved in glycerol uptake - unknown function | plasma membrane |
| ADY2
| Probable plasma membrane acetate permease, similar to Yarrowia lipolytica Gpr1 | plasma membrane |
| ATO3
| Protein similar to Ady2, a probable plasma membrane acetate permease | plasma membrane |
| FUI1
| Uridine permease | plasma membrane |
| FLR1
| Putative H+ antiporter regulated by yAP-1 and involved in multidrug resistance | plasma membrane |
| FUR4
| Uracil permease | plasma membrane |
| QDR3
| Putative substrate-H+ antiporter - confers resistance to several drugs | plasma membrane |
| BAP2
| Broad-specificity amino-acid permease - inductible by most neutral amino acids | plasma membrane |
| TAT1
| Broad-specificity amino-acid permease | plasma membrane |
| YMC2
| Member of the mitochondrial carrier (MCF) family - unknown function | plasma membrane |
| AGP2
| Plasma membrane protein with proposed role in carnitine, polyamine and amino-acid transport | plasma membrane |
| DTR1
| bisformyl dityrosine-H+ antiporter of the plasma membrane - involved in excretion of bisformyl dityrosine to the maturing spore wall | plasma membrane |
| SUL1
| Sulfate permease I | plasma membrane |
| PHO89
| Na+/phosphate co-transporter | plasma membrane |
| MAL61
| Maltose permease | plasma membrane |
| AGP1
| Broad-specificity, relatively-low-affinity, amino-acid permease - inductible by most neutral amino acids | plasma membrane |
| GEX1
| Plasma membrane and vacuolar membrane glutathione/H+ antiporter | plasma membrane |
| FEN2
| Pantothenate permease | plasma membrane |
| PHO87
| Low affinity phosphate transporter | plasma membrane |
| GIT1
| Glycerophosphoinositol transporter also able to mediate low-affinity phosphate transport | plasma membrane |
| RGT2
| Sensor of high external glucose concentrations | plasma membrane |
| SNF3
| Sensor of low external glucose concentrations | plasma membrane |
| UGA4
| GABA permease - also involved in delta-aminolevulinate transport | plasma membrane |
| HXT15
| Hxt family protein with intrinsic hexose transport activity - unknown physiological function | plasma membrane |
| YDL247W
| Protein of the maltose transporter family with hexose transport activity - unknown physiological function | plasma membrane |
| BAP3
| Broad-specificity amino-acid permease - inductible by most neutral amino acids | plasma membrane |
| YDR090C
| Protein similar to the human lysosomal CTNS cystine transporter mediating H+-driven cystine export from lysosomes - unknown function | plasma membrane |
| SSY1
| Sensor of extracellular amino acids - member of the amino acid permease family | plasma membrane |
| HXT7
| High-affinity hexose facilitator | plasma membrane |
| HXT6
| High-affinity hexose facilitator | plasma membrane |
| HXT3
| Low-affinity hexose facilitator | plasma membrane |
| ITR1
| Inositol permease | plasma membrane |
| GNP1
| Broad-specificity amino-acid permease | plasma membrane |
| STL1
| Glycerol permease | plasma membrane |
| CAN1
| Arginine permease | plasma membrane |
| SIT1
| Transporter of the bacterial siderophore ferrioxamine B | plasma membrane |
| HXT13
| Hxt family protein with intrinsic hexose transport activity - unknown physiological function | plasma membrane |
| FCY2
| Purine/cytosine permease | plasma membrane |
| HXT10
| Hxt family protein with intrinsic hexose transport activity - unknown physiological function | plasma membrane |
| HNM1
| Choline permease | plasma membrane |
| TPN1
| Pyridoxine (vitamin B6) transporter | plasma membrane |
| ZRT1
| Zinc transporter I | plasma membrane |
| MUP1
| High affinity methionine permease | plasma membrane |
| VHT1
| Biotin (vitamin H) permease | plasma membrane |
| TPO2
| Proposed vacuolar polyamine transporter | plasma membrane |
| HIP1
| Histidine permease | plasma membrane |
| AZR1
| Putative substrate-H+ antiporter involved in resistance to azole and acetic acid | plasma membrane |
| TNA1
| Nicotinic acid permease | plasma membrane |
| AGT1
| Alpha-glucoside and threhalose permease | plasma membrane |
| DUR3
| Urea permease | plasma membrane |
| SMF2
| Transporter of divalent metal cations (manganese, copper, iron) | plasma membrane |
| HXT4
| Hexose facilitator of moderately low affinity | plasma membrane |
| HXT1
| Low-affinity hexose facilitator | plasma membrane |
| HXT5
| Hxt family protein with intrinsic hexose transport activity | plasma membrane |
| QDR1
| Putative substrate-H+ antiporter involved in resistance to ketoconazole and quinidine | plasma membrane |
| QDR2
| Putative substrate-H+ antiporter - confers resistance to quinidine | plasma membrane |
| DAL4
| Allantoin permease | plasma membrane |
| TRK1
| Potassium transporter I | plasma membrane |
| PHO90
| Low affinity phosphate transporter | plasma membrane |
| HGT1
| Tetra- and pentapeptide permease - high-affinity glutathione transporter | plasma membrane |
| HXT9
| Hxt family protein with intrinsic hexose transport activity - unknown physiological function | plasma membrane |
| DAL5
| Allantoate and ureidosuccinate permease - also involved in uptake of dipeptides | plasma membrane |
| HXT16
| Hxt family protein with intrinsic hexose transport activity - unknown physiological function | plasma membrane |
| YJR160C
| Protein of the maltose transporter family with hexose transport activity - unknown physiological function | plasma membrane |
| JEN1
| Lactate and pyruvate permease | plasma membrane |
| GAP1
| General amino acid permease | plasma membrane |
| TRK2
| Potassium transporter II | plasma membrane |
| PTR2
| Di- and tripeptide permease | plasma membrane |
| TPO1
| Plasma membrane polyamine-H+ antiporter | plasma membrane |
| YCT1
| Plasma membrane specific L-cysteine permease | plasma membrane |
| MMP1
| s-methylmethionine permease | plasma membrane |
| GAL2
| Galactose permease | plasma membrane |
| SUL2
| Sulfate permease II | plasma membrane |
| ZRT2
| Zinc transporter II | plasma membrane |
| NHA1
| Na+/H+ exchanger (also harbouring K+/H+ activity) | plasma membrane |
| THI10
| Thiamine permase | plasma membrane |
| ATR1
| Putative substrate-H+ antiporter conferring resistance to aminotriazole, proposed boron transporter. | plasma membrane |
| PHO84
| Inorganic phosphate permease | plasma membrane |
| HXT2
| Hexose facilitator of moderately low affinity for glucose | plasma membrane |
| LYP1
| Lysine permease | plasma membrane |
| BOR1
| Protein involved in boron efflux - strongly similar to transporters of the anion exchanger family (band 3 protein) | plasma membrane |
| PHO91
| Low affinity phosphate transporter | plasma membrane |
| HOL1
| Putative substrate-H+ antiporter - unknown biological function | plasma membrane |
| BIO5
| Plasma mmebrane 7-keto 8-aminopelargonic acid permease | plasma membrane |
| HXT17
| Hxt family protein with intrinsic hexose transport activity - unknown physiological function | plasma membrane |
| TAT2
| Broad-specificity amino-acid permease - inductible by most neutral amino acids | plasma membrane |
| ITR2
| Inositol permease | plasma membrane |
| SMF1
| Manganese transporter of the plasma membrane | plasma membrane |
| HXT11
| Hxt family protein with intrinsic hexose transport activity - unknown physiological function | plasma membrane |
| ENB1
| Transporter of the siderophore enterobactin | plasma membrane |
| NRT1
| Nicotinamide riboside permease - has also low-affinity for thiamine | plasma membrane |
| TPO4
| Proposed vacuolar polyamine transporter | plasma membrane |
| MCH5
| Riboflavin (vitamin B2) permease | plasma membrane |
| PUT4
| Proline permease | plasma membrane |
| SSU1
| Protein proposed to mediate excretion of sulfite | plasma membrane |
| DIP5
| Glutamate and aspartate permease - able to mediate transport of other amino acids | plasma membrane |
| SAM3
| S-adenosylmethionine permease | plasma membrane |
| TPO3
| Proposed vacuolar polyamine transporter | plasma membrane |
| OPT2
| Tetra- and pentapeptide permease | plasma membrane |
| SGE1
| Putative substrate-H+ antiporter conferring resistance to crystal violet and to 10-N-nonyl acridine orange (NAO) | plasma membrane |
| ACR3
| Probable arsenite extrusion protein | plasma membrane |
| YML038C
| Putative transporter of the triose phosphate translocator family - unknown function | secretory pathway membrane |
