ARID4A

[edit] synopsis of the potential involvement in CHD

In a patient with a TGA, microtia, microphthalmia and polydactyly, a deletion on 14q21.3 was identified (Thienpont et al). Prioritisation of the genes in the deleted region resulted in a high ranking of ARID4A. Therefore the expression pattern of ARID4A was investigated in zebrafish. This showed only weak ubiquitous expression throughout development, suggesting that ARID4A does not play an important role in zebrafish cardiac development.

External references for ARID4A

• ensembl: ENSG00000032219
• OMIM: 180201
• Search miRBase for ARID4A
• Expression patterns from 4DXPress: ARID4A
• MGI: MGI:2444354
• ZFIN:
• Wikipedia: ARID4A
• Search Wikiproteins: ARID4A
• Search Genetic Association Database: ARID4A
• Search GeneTests: ARID4A
• CHeartED:

Known phenotypes for ARID4A

Non-syndromic

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Syndromic

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Protein interaction partners

Patients reports for ARID4A

• case 1301 Clinical data Phenotype

Translocations

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Mutations in ARID4A

Representation of protein ARID4A

Heart expression domain of ARID4A

No specified expression domain for ARID4A

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Associated CHDs found by automated text mining

AGeneApart Method

Huge Navigator (Genopedia)

See complete results on Genopedia (including non CHD)

Heart defects